Synaptic transmission and plasticity

I’m focused in the analysis of mechanisms and physiological processes occurring within intricate neural networks, meticulously examining both developmental stages and adulthood. My primary focus lies in the study of brain dysfunctions and neurodegenerative diseases, including epilepsy, Alzheimer's and other forms of senile dementia. Specifically, I have conducted in-depth investigations into physiopathological mechanisms using a murine model for Alzheimer's research. I have explored the impacts of new molecules on synaptic plasticity, evaluating their potential use in the treatment of patients affected by neurodegenerative pathologies associated with aging. My primary objective is to contribute significantly to scientific knowledge in the field of neuroscience, focusing on delving into crucial aspects such as synaptic plasticity and cognitive processes. This work aims to enhance the understanding of the physiological foundations of brain functions and related pathological conditions, with the ultimate goal of advancing research and therapies in this complex field.

Members:
Michele Fiore
Alessandra Picollo