Personal Card



Mario D'acunto

Research staff

during the course of his scientific career, he has made pioneering contributions in the areas of Nanotribology, Nano-optics and Nanophotonics and Scanning Probe Microscopy, essentially Atomic Force Microscopy and Near-Field Optical Scanning Microscopy and Nonlinear Dynamical Systems. Dr D’Acunto’s scientific accomplishments include the first model ever proposed for Onset Wear on atomic scale; Near-Field Plasmonic behaviour of metal nanoparticles interacting with biological systems, Raman Scattering and Imaging applied to oncology, Quantum biology. More information can be found on web site http://www.pi.ibf.cnr.it/?page_id=2115 together with comprehensive publication lists.

orcid://0000-0003-4233-1943,

Contact:

- Email mario.dacunto@ibf.cnr.it
- Phone +39-050-3152763
- Location Pisa

Website:

http://www.pi.ibf.cnr.it/?page_id=2115

Research interests:

- Bioplasmonics and Scanning Probe Microscopy (Principal investigator)
- TELEMO (An innovative TELEmedicine system for the early screening of Melanoma in Overall Population) (Principal investigator)
- STOP-VIRUS (Principal investigator)
- Trp phosphorescence spectroscopy applied to the study of protein structure and dynamics.
- Interaction of proteins with nanoparticles

Further collaborations:

- CNR-ISTI
-
- CNR-ISM
-
- UNIPI
-
- McGill University Canada

Financial support:

- NanoClear supported by Regione Toscana (started 2024)
-
- PNRR PE4 National Quantum Science and Technology Institute ( started 2022)
-
- TELEMO ( Raman Spectrscopy and Oncology diagnois on Melanoma Cancer) supported by Regione Toscana Bando Salute 2018 ( started 2020 )

Key publications:

Exploiting Gold Nanoparticles for Diagnosis and Cancer Treatments

Protein-DNA target search relies on quantum walk

Contribution of Raman Spectroscopy to Diagnosis and Grading of Chondrogenic Tumors

From human mesenchymal stromal cells to osteosarcoma cells classification by deep learning

In Situ Surface-Enhanced Raman Spectroscopy of Cellular Components: Theory and Experimental Results

Publications (45):

Conjugation to gold nanoparticles of methionine gamma-lyase, a cancer-starving enzyme. Physicochemical characterization of the nanocomplex for prospective nanomedicine applications
Raboni, S.; Fumagalli, F.; Ceccone, G.; La Spina, R.; Ponti, J.; Mehn, D.; Guerrini, G.; Bettati, S.; Mozzarelli, A.; D'Acunto, M.; Presciuttini, G.; Cristallini, C.; Gabellieri, E.; Cioni, P.
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 653, 2024
DOI: 10.1016/j.ijpharm.2024.123882

Incorporation of Copper Nanoparticles on Electrospun Polyurethane Membrane Fibers by a Spray Method
Al Kayal, Tamer; Giuntoli, Giulia; Cavallo, Aida; Pisani, Anissa; Mazzetti, Paola; Fonnesu, Rossella; Rosellini, Alfredo; Pistello, Mauro; D'Acunto, Mario; Soldani, Giorgio; Losi, Paola
MOLECULES, 28, 2023
DOI: 10.3390/molecules28165981

Quantum Computation by Biological Systems
D'Acunto, Mario
IEEE TRANSACTIONS ON MOLECULAR, BIOLOGICAL, AND MULTI-SCALE COMMUNICATIONS, 9, 2023
DOI: 10.1109/TMBMC.2023.3272230

Raman spectroscopy and topological machine learning for cancer grading
Conti F.; D'Acunto M.; Caudai C.; Colantonio C.; Gaeta R.; Moroni D.; Pascali M.A.
SCIENTIFIC REPORTS, 13, 2023
DOI: 10.1038/s41598-023-34457-5

A Copper nanoparticles-based polymeric spray coating: Nanoshield against Sars-Cov-2
Foffa, Ilenia and Losi, Paola and Quaranta, Paola and Cara, Alice and Al Kayal, Tamer and D'Acunto, Mario and Presciuttini, Gianluca and Pistello, Mauro and Soldani, Giorgio
j appl biomater function mater, 20, 2022
DOI: 10.1177/22808000221076326

Deep Learning for Chondrogenic Tumor Classification through Wavelet Transform of Raman Spectra
Conforti Pietro, Manganelli; D'Acunto, Mario; Russo, Paolo
SENSORS (BASEL), 22, 2022
DOI: 10.3390/s22197492

Quantum biology. pi-pi entanglement signatures in protein-DNA interactions
D'Acunto, Mario
physical biology (print), 19, 2022
DOI: 10.1088/1478-3975/ac5bda

Exploiting gold nanoparticles for diagnosis and cancer treatments
D'Acunto, Mario and Cioni, Patrizia and Gabellieri, Edi and Presciuttini, Gianluca
nanotechnology (bristol. print), 32, 2021
DOI: 10.1088/1361-6528/abe1ed

Poly(vinyl alcohol)/Gelatin Scaffolds Allow Regeneration of Nasal Tissues
D'Alessandro, Delfo and Moscato, Stefania and Fusco, Alessandra and De la Ossa, Jose Gustavo and D'Acunto, Mario and Trombi, Luisa and Feula, Marta and Serino, Lorenzo Pio and Donnarumma, Giovanna and Petrini, Mario and Berrettini, Stefano and Danti, Serena
applied sciences, 11, 2021
DOI: 10.3390/app11083651

Protein-DNA target search relies on quantum walk
D'Acunto M.
biosystems (amst. print)issn: 0303-2647elsevier science ireland, 201, 2021
DOI: 10.1016/j.biosystems.2020.104340

Advanced Infrared Technology and Applications 2020: introduction to the feature issue
Strojnik, Marija; D'Acunto, Mario; Rogalski, Antoni
Applied Optics, 59, 2020
DOI: 10.1364/AO.398348

Contribution of Raman Spectroscopy to Diagnosis and Grading of Chondrogenic Tumors
D'Acunto, Mario; Gaeta, Raffaele; Capanna, Rodolfo; Franchi, Alessandro
Scientific Reports, 10, 2020
DOI: 10.1038/s41598-020-58848-0

Optimized Dislocation of Mobile Sensor Networks on Large Marine Environments Using Voronoi Partitions
D'Acunto, Mario; Moroni, Davide; Puntoni, Alessandro; Salvetti, Ovidio
Journal Of Marine Science And Engineering, 8, 2020
DOI: 10.3390/jmse8020132

An E-Nose for the Monitoring of Severe Liver Impairment: A Preliminary Study
Germanese D, Colantonio S, D'Acunto M, Romagnoli V, Salvati A, Brunetto M
Sensors, 19, 2019
DOI: 10.3390/s19173656

From human mesenchymal stromal cells to osteosarcoma cells classification by deep learning
D'Acunto M.; Martinelli M.; Moroni D.
journal of intelligent & fuzzy systems, 37, 2019
DOI: 10.3233/JIFS-179332

In Situ Surface-Enhanced Raman Spectroscopy of Cellular Components: Theory and Experimental Results
D'Acunto M
Materials, 12, 2019
DOI: 10.3390/ma12091564

Raman spectroscopy of osteosarcoma cells
D'Acunto M, Trombi L, D'Alessandro D, Danti S
Physical biology, 16, 2019
DOI: 10.1088/1478-3975/aaefbf

Detection of intracellular gold nanoparticles: An overview
D'Acunto M
Materials , 11, 2018
DOI: 10.3390/ma11060882

Cardio-metabolic diseases prevention by self-monitoring the breath
Germanese D; D'Acunto M.; Magrini M.; Righi M.; Salvetti O.
IFSA-news, 215, 2017

Design, fabrication and characterization of composite piezoelectric ultrafine fibers for cochlear stimulation
Mota, Carlos; Labardi, Massimiliano; Trombi, Luisa; Astolfi, Laura; D'Acunto, Mario; Puppi, Dario; Gallone, Giuseppe; Chiellini, Federica; Berrettini, Stefano; Bruschini, Luca; Danti, Serena
MATERIALS & DESIGN, 122, 2017
DOI: 10.1016/j.matdes.2017.03.013

Mirror Mirror on the Wall ... An Unobtrusive Intelligent Multisensory Mirror for Well-Being Status Self-Assessment and Visualization
Henriquez, P; Matuszewski, B J; Andreucabedo, Y; Bastiani, L; Colantonio, S; Coppini, G; D'Acunto, M; Favilla, R; Germanese, D; Giorgi, D; Marraccini, P; Martinelli, M; Morales, MARIA AURORA; Pascali, MARIA ANTONIETTA; Righi, M; Salvetti, O; Larsson, M; Stromberg, T; Randeberg, L; Bjorgan, A; Giannakakis, G; Pediaditis, M; Chiarugi, F; Christinaki, E; Marias, K; Tsiknakis, M
IEEE TRANSACTIONS ON MULTIMEDIA, 19, 2017
DOI: 10.1109/TMM.2017.2666545

Near-field surface plasmon field enhancement induced by rippled surfaces
D'Acunto M, Fuso F, Micheletto R, Naruse M, Tantussi F, Allegrini M
Beilstein journal of nanotechnology, 8, 2017
DOI: 10.3762/bjnano.8.97

The wize sniffer knows what you did: prevent cardio-metabolic risk by analyzing your breath
Germanese D.; D'Acunto M.; Righi M.; Magrini M.; Salvetti O.
INTERNATIONAL JOURNAL ON ADVANCES IN LIFE SCIENCES, 9, 2017

A new method combining enhanced resolution and pattern identification
D'Acunto, M; Righi, M; Salvetti, O
SIGNAL, IMAGE AND VIDEO PROCESSING (INTERNET), 10, 2016
DOI: 10.1007/s11760-016-0947-9

Advances in infrared technology and applications: introduction
Strojnik, M; D'Acunto, M; Rogalski, A
APPLIED OPTICS (2004, ONLINE), 55, 2016
DOI: 10.1364/AO.55.00ITA1

An image enhancement tool: pattern recognition image augmented resolution
Righi M.; D'Acunto M.; Salvetti O.
PATTERN RECOGNITION AND IMAGE ANALYSIS, 26, 2016
DOI: 10.1134/S1054661816030160

Detection and localization of gold nanoshells inside cells: near-field approximation
D'Acunto, M; Cricenti, A; Danti, S; Dinarelli, S; Luce, M; Moroni, D; Salvetti, O
APPLIED OPTICS (2004), 55, 2016
DOI: 10.1364/AO.55.000D11

Nanoscale rippling on polymer surfaces induced by AFM manipulation
D'Acunto, M; Dinelli, F; Pingue, P
BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 6, 2015
DOI: 10.3762/bjnano.6.234

Optical detection of core-gold nanoshells inside biosystems
D'Acunto, M; Cricenti, A; Luce, M; Dinarelli, S
NANOSPECTROSCOPY, 1, 2015
DOI: 10.1515/nansp-2015-0007

Theory of near-field detection of core-gold nanoshells inside biosystems
D'Acunto, M; Cricenti, A; Luce, M; Dinarelli, S
COMPUTER MODELLING AND NEW TECHNOLOGIES, 19, 2015

Ultra small clusters of gold nanoshells detected by SNOM
D'Acunto M.; Cricenti A.; Luce M.; Moroni D.; Salvetti O.
OPTO-ELECTRONICS REVIEW, 23, 2015
DOI: 10.1515/oere-2015-0010

3D image reconstruction using Radon transform
D'Acunto M.; Benassi A.; Moroni D.; Salvetti O.
SIGNAL, IMAGE AND VIDEO PROCESSING (PRINT), 2014
DOI: 10.1007/s11760-014-0693-9

A methodological approach for combining super-resolution and pattern-recognition to image identification
D'Acunto, M; Pieri, G; Righi, M; Salvetti, O
PATTERN RECOGNITION AND IMAGE ANALYSIS, 24, 2014
DOI: 10.1134/S1054661814020023

Boron nitride nanotube-functionalised myoblast/microfibre constructs: a nanotech-assisted tissue engineered platform for muscle stimulation
Danti S.; Ciofani G.; Pertici G.; Moscato S.; D'Alessandro D.; Ciabatti E.; Chiellini F.; D'Acunto M.; Mattoli V.; Berrettini S.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2014
DOI: 10.1002/term.1878

NanoICT: a new challenge for ICT
D'Acunto M.; Benassi A.; Salvetti O.
ERCIM NEWS, 89, 2012

Nanoscale biomolecular detection limit for gold nanoparticles based on near-infrared response
D'Acunto, M; Moroni, D; Salvetti, O
ADVANCES IN OPTICAL TECHNOLOGIES (ONLINE), 2012, 2012
DOI: 10.1155/2012/278194

Bioactive polyurethanes in clinical applications
Ciardelli, Gianluca; Rechichi, A; Sartori, S; D'Acunto, M; Caporale, A; Peggion, E; Vozzi, G; Giusti, P
POLYMERS FOR ADVANCED TECHNOLOGIES (ONLINE), 17, 2011
DOI: 10.1002/pat.781

Good manufacturing practices-grade preformed ossicular prostheses from banked bone via computer numerically controlled micromilling
Berrettini, Stefano; Bruschini, Luca; Stefanini, Cesare; D'Alessandro, Delfo; D'Acunto, Mario; Danti, Serena
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 120, 2011
DOI: 10.1177/000348941112000102

Nanovectors for drug delivery: long-lived pore dynamics for swelling liposomes
D'Acunto, Mario
MECHANICS RESEARCH COMMUNICATIONS, 38, 2011
DOI: 10.1016/j.mechrescom.2010.11.002

Pattern recognition methods for thermal drift correction in atomic force microscopy imaging
D'Acunto, M; Salvetti, O
PATTERN RECOGNITION AND IMAGE ANALYSIS, 21, 2011
DOI: 10.1134/S1054661811010056

Poly(ester urethane) guides for peripheral nerve regeneration
Chiono, Valeria; Sartori, Susanna; Rechichi, Alfonsina; Tondaturo, Chiara; Vozzi, Giovanni; Vozzi, Federico; D'Acunto, Mario; Salvadori, Claudia; Dini, Francesca; Barsotti, Giovanni; Carlucci, Fabio; Burchielli, Silvia; Nicolino, Silvia; Audisio, Chiara; Perroteau, Isabelle; Giusti, Paolo; Ciardelli, Gianluca
MACROMOLECULAR BIOSCIENCE (PRINT), 11, 2011
DOI: 10.1002/mabi.201000354

New bioartificial systems and biodegradable synthetic polymers for cardiac tissue engineering: a preliminary screening
Rosellini E.; Cristallini C.; Barbani N.; Vozzi G.; D'Acunto M.; Ciardelli G.; Giusti P.
DOI: 10.4015/S1016237210002249

Acrylic copolymers as candidates for drug eluting coating of vascular stents
Silvestri, D; Cristallini, C; Gagliardi, M; D'Acunto, M; Barbani, N; Ciardelli, G; Giusti, P
JOURNAL OF BIOMATERIALS APPLICATIONS, 24, 2009

Surface modification of a synthetic polyurethane by plasma glow discharge: Preparation and characterization of bioactive monolayers
Sartori, S; Rechichi, A; Vozzi, G; D'Acunto, M; Heine, E; Giusti, P; Ciardelli, G
REACTIVE & FUNCTIONAL POLYMERS, 68, 2008
DOI: 10.1016/j.reactfunctpolym.2007.12.002

Influence of a reduced mobility layer on the structural relaxation dynamics of alluminum capped ultrathin film of polye(ethylene terephthalate)
Napolitano, S; Prevosto, D; Lucchesi, M; Pingue, P; D'Acunto, M; Rolla, Pa
LANGMUIR, 23,, 2007
DOI: 10.1021/la062229j