Personal Card

Cesare Usai


1970 Degree in Physics, Univ. of Genoa, Italy 1973 Researcher, IBF-CNR, Genoa 1985-86 Visiting scientist, Dept. Biophys. & Med. Phys., Univ. of California, Berkeley 1989 Senior Researcher, IBF-CNR, Genoa Since 2010 Research Associate, IBF-CNR, Genoa Interest: molecular mechanisms in the synaptic transmission in pathological (ALS) mammalian neurons and astrocytes. (Coll. with the Dept. of Pharmacy, Univ. of Genoa) Teaching: Adjunct Professor, Univ. of Genoa, School of Mathematical, Physical and Natural Sciences Reviewer: J Neurochem; J Microscopy; Micr Res & Tech; Int J Biochem & Cell Biol; J Biomed Opt; Exp Clin Pharmacol; J Neurosci Res Awards: Special Award Leica Microsystem: 1st Prize for the most innovative service: Power up your Microscope



- Email
- Phone +39-010-6475579
- Location Genova

Further collaborations:

- Giambattista Bonanno (Univ. of Genoa, School of Medical and Pharmachological Sciences, Dept. of Pharmacy, Genoa)
- Anna Pittaluga (Univ. of Genoa, School of Medical and Pharmachological Sciences, Dept. of Pharmacy, Genoa)

Key publications:

Role of miRNAs shuttled by mesenchymal stem cell?derived small extracellular vesicles in modulating neuroinflammation Debora Giunti, Chiara Marini, Benedetta Parodi, Cesare Usai, Marco Milanese, Giambattista Bonanno, Nicole Kerlero de Rosbo & Antonio Uccelli, Scientific Reports | (2021) 11:1740 |

Antibodies Against the NH2-Terminus of the GluA Subunits Affect the AMPA-Evoked Releasing Activity: The Role of Complement Francesca Cisani, Guendalina Olivero, Cesare Usai, Gilles Van Camp, Stefania Maccari, Sara Morley-Fletcher and Anna Maria Pittaluga, Frontiers in Immunology 26 February 2021 | Volume 12 | doi: 10.3389/fimmu.2021.586521

Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression Tiziana Bonifacino, Claudia Rebosio, Francesca Provenzano, Carola Torazza, Matilde Balbi, Marco Milanese, Luca Raiteri, Cesare Usai, Ernesto Fedele and Giambattista Bonanno, Int. J. Mol. Sci. 2019, 20, 4552; doi:10.3390/ijms20184552

Immuno-Pharmacological Characterization of Presynaptic GluN3A-Containing NMDA Autoreceptors: Relevance to Anti-NMDA Receptor Autoimmune Diseases Guendalina Olivero, Matteo Vergassola, Francesca Cisani1, Cesare Usai, and Anna Pittaluga, Molecular Neurobiology, Accepted: 24 January 2019,

The effect of pulsed electromagnetic field exposure on osteoinduction of human mesenchymal stem cells cultured on nano-TiO2 surfaces Nora Bloise, Loredana Petecchia, Gabriele Ceccarelli, Lorenzo Fassina, Cesare Usai, Federico Bertoglio, Martina Balli, Massimo Vassalli, Maria Gabriella Cusella De Angelis4 Paola Gavazzo3 Marcello Imbriani, Livia Visai, PLOS ONE | June 14, 2018

Publications (83):

Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation
Giunti D.; Marini C.; Parodi B.; Usai C.; Milanese M.; Bonanno G.; Kerlero de Rosbo N.; Uccelli A.
Scientific reports (Nature Publishing Group), 2021
DOI: 10.1038/s41598-021-81039-4

Antibodies Against the NH2-Terminus of the GluA Subunits Affect the AMPA-Evoked Releasing Activity: The Role of Complement
Cisani F.; Olivero G.; Usai C.; Van Camp G.; Maccari S.; Morley-Fletcher S.; Pittaluga A.M.
Frontiers in immunology, 2021
DOI: 10.3389/fimmu.2021.586521

Immuno-Pharmacological Characterization of Presynaptic GluN3A-Containing NMDA Autoreceptors: Relevance to Anti-NMDA Receptor Autoimmune Diseases
Olivero G, Vergassola M, Cisani F, Usai C, Pittaluga A
Molecular neurobiology, 2019
DOI: 10.1007/s12035-019-1511-8

Altered glucose catabolism in the presynaptic and perisynaptic compartments of SOD1G93A mouse spinal cord and motor cortex indicates that mitochondria are the site of bioenergetic imbalance in ALS
Ravera S.; Torazza C.; Bonifacino T.; Provenzano F.; Rebosio C.; Milanese M.; Usai C.; Panfoli I. and Bonanno G.
Journal of neurochemistry, 2019
DOI: 10.1111/jnc.14819

Enhanced function and overexpression of metabotropic glutamate receptors 1 and 5 in the spinal Cord of the SOD1G93A mouse model of amyotrophic lateral sclerosis during disease progression
Bonifacino T.; Rebosio C.; Provenzano F.; Torazza C.; Balbi M.; Milanese M.; Raiteri L.; Usai C.; Fedele E.; Bonanno G.
International journal of molecular sciences (Print), 2019
DOI: 10.3390/ijms20184552

The effect of pulsed electromagnetic field exposure on osteoinduction of human mesenchymal stem cells cultured on nano-TiO2 surfaces
Bloise N, Petecchia L, Ceccarelli G, Fassina L, Usai C, Bertoglio F, Balli M, Vassalli M, Cusella De Angelis MG, Gavazzo P, Imbriani M, Visai L
PloS one, 2018
DOI: 10.1371/journal.pone.0199046

5-HT2A-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT2A to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis
Olivero G, Grilli M, Vergassola M, Bonfiglio T, Padolecchia C, Garrone B, Di Giorgio FP, Tongiani S, Usai C, Marchi M, Pittaluga A
Neuropharmacology, 2018
DOI: 10.1016/j.neuropharm.2018.02.030

Presynaptic mGlu1 Receptors Control GABAB Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings
Vergassola M, Olivero G, Cisani F, Usai C, Bossi S, Puliti A, Pittaluga A
Frontiers in molecular neuroscience, 2018
DOI: 10.3389/fnmol.2018.00324

Biophysical characterization of nanostructured TiO2 as a good substrate for hBM-MSC adhesion, growth and differentiation
Petecchia L, Usai C, Vassalli M, Gavazzo P
Experimental cell research, 2017
DOI: 10.1016/j.yexcr.2017.06.008

In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis
Bonifacino T, Cattaneo L, Gallia E, Puliti A, Melone M, Provenzano F, Bossi S, Musante I, Usai C, Conti F, Bonanno G, Milanese M
Neuropharmacology, 2017
DOI: 10.1016/j.neuropharm.2017.06.020

G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2
Fresia C, Vigliarolo T, Guida L, Booz V, Bruzzone S, Sturla L, Di Bona M, Pesce M, Usai C, De Flora A, Zocchi E
Scientific reports (Nature Publishing Group), 2016
DOI: 10.1038/srep26658

Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome
Ravera S, Dufour C, Cesaro S, Bottega R, Faleschini M, Cuccarolo P, Corsolini F, Usai C, Columbaro M, Cipolli M, Savoia A, Degan P, Cappelli E
Scientific reports (Nature Publishing Group), 2016
DOI: 10.1038/srep25441

Presynaptic, release-regulating mGlu(2)-preferring and mGlu(3)-preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease
Di Prisco S, Merega E, Bonfiglio T, Olivero G, Cervetto C, Grilli M, Usai C, Marchi M, Pittaluga A
British journal of pharmacology, 2016
DOI: 10.1111/bph.13442

Bradykinin B2 receptor expression in the bronchial mucosa of allergic asthmatics: The role of NF-kB
Ricciardolo FL, Petecchia L, Sorbello V, Di Stefano A, Usai C, Massaglia GM, Gnemmi I, Mognetti B, Hiemstra PS, Sterk PJ, Sabatini F
Clinical and experimental allergy (Print), 2016
DOI: 10.1111/cea.12676

Colocalization of neurotransmitter transporters on the plasma membrane of the same nerve terminal may reflect cotransmission
Romei C, Bonifacino T, Milanese M, Usai C, Raiteri L
Brain research bulletin (Online), 2016
DOI: 10.1016/j.brainresbull.2016.08.013

Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: A mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis
Milanese M.; Bonifacino T.; Fedele E.; Rebosio C.; Cattaneo L.; Benfenati F.; Usai C.; Bonanno G.
Neurobiology of disease, 2015
DOI: 10.1016/j.nbd.2014.12.004

The enzymatic activities of CD38 enhance CLL growth and trafficking: Implications for therapeutic targeting
Vaisitti T.; Audrito V.; Serra S.; Buonincontri R.; Sociali G.; Mannino E.; Pagnani A.; Zucchetto A.; Tissino E.; Vitale C.; Coscia M.; Usai C.; Pepper C.; Gattei V.; Bruzzone S.; Deaglio S.
Leukemia, 2015
DOI: 10.1038/leu.2014.207

Dysregulated Ca2+ Homeostasis in Fanconi anemia cells
Usai, Cesare; Ravera, Silvia; Cuccarolo, Paola; Panfoli, Isabella; Dufour, Carlo; Cappelli, Enrico; Degan, Paolo
Scientific reports (Nature Publishing Group), 2015
DOI: 10.1038/srep08088

Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS
Parodi B.; Rossi S.; Morando S.; Cordano C.; Bragoni A.; Motta C.; Usai C.; Wipke B.T.; Scannevin R.H.; Mancardi G.L.; Centonze D.; Kerlero de Rosbo N.; Uccelli A.
Acta neuropathologica, 2015
DOI: 10.1007/s00401-015-1422-3

Electro-magnetic field promotes osteogenic differentiation of BM-hMSCs through a selective action on Ca2+-related mechanisms
Petecchia, Loredana; Sbrana, Francesca; Utzeri, Roberto; Vercellino, Marco; Usai, Cesare; Visai, Livia; Vassalli, Massimo; Gavazzo, Paola
Scientific reports (Nature Publishing Group), 2015
DOI: 10.1038/srep13856

Pharmacological characterization of NMDA-like receptors in the single-celled organism Paramecium primaurelia
Ramoino, Paola; Candiani, Simona; Pittaluga, Anna Maria; Usai, Cesare; Gallus, Lorenzo; Ferrando, Sara; Milanese, Marco; Faimali, Marco; Bonanno, Giambattista
Journal of experimental biology, 2014
DOI: 10.1242/jeb.093914

A new function for glycine GlyT2 transporters: Stimulation of ?-aminobutyric acid release from cerebellar nerve terminals through GAT1 transporter reversal and Ca2+-dependent anion channels
Milanese M.; Romei C.; Usai C.; Oliveri M.; Raiteri L.
Journal of neuroscience research, 2014
DOI: 10.1002/jnr.23321

Presynaptic mGlu7 receptors control GABA release in mouse hippocampus
Summa M; Di Prisco S; Grilli M; Usai C; Marchi M; Pittaluga A
Neuropharmacology, 2013
DOI: 10.1016/j.neuropharm.2012.04.020

Group I metabotropic glutamate autoreceptors induce abnormal glutamate exocytosis in a mouse model of amyotrophic lateral sclerosis
Giribaldi F; Milanese M; Bonifacino T; Anna Rossi PI; Di Prisco S; Pittaluga A; Tacchetti C; Puliti A; Usai C; Bonanno G
Neuropharmacology, 2013
DOI: 10.1016/j.neuropharm.2012.05.018

Mesenchymal Stem Cells Shape Microglia Effector Functions Through the Release of CX3CL1
Giunti D; Parodi B; Usai C; Vergani L; Casazza S; Bruzzone S; Mancardi G; Uccelli A
Stem cells (Dayt. Ohio), 2012
DOI: 10.1002/stem.1174

In vitro exposure to nicotine induces endocytosis of presynaptic AMPA receptors modulating dopamine release in rat nucleus accumbens nerve terminals
Grilli M; Summa M; Salamone A; Olivero G; Zappettini S; Di Prisco S; Feligioni M; Usai C; Pittaluga A; Marchi M
Neuropharmacology, 2012
DOI: 10.1016/j.neuropharm.2012.06.049

Autocrine abscisic acid plays a key role in quartz-induced macrophage activation
Magnone M; Sturla L; Jacchetti E; Scarfì S; Bruzzone S; Usai C; Guida L; Salis A; Damonte G; De Flora A; Zocchi E
The FASEB journal, 2012
DOI: 10.1096/fj.11-187351

Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway
Petecchia L; Sabatini F; Usai C; Caci E; Varesio L; Rossi GA
Laboratory investigation (Print), 2012
DOI: 10.1038/labinvest.2012.67

Pharmacological Modulation of the Bradykinin-Induced Differentiation of Human Lung Fibroblasts: Effects of Budesonide and Formoterol
Sabatini F; Petecchia L; Usai C; Silvestri M; Rossi GA; Miller-Larsson A; Ricciardolo FL
The Journal of asthma, 2012
DOI: 10.3109/02770903.2012.729633

The endocannabinoid system in rat gliosomes and its role in the modulation of glutamate release
Bari M, Bonifacino T, Milanese M, Spagnuolo P, Zappettini S, Battista N, Giribaldi F, Usai C, Bonanno G, Maccarrone M
Cellular and molecular life sciences (Print. ed.), 2011

Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis
Milanese M, Zappettini S, Onofri F, Musazzi L, Tardito D, Bonifacino T, Messa M, Racagni G, Usai C, Benfenati F, Popoli M, Bonanno G
Journal of neurochemistry, 2011

Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD(+) Release and P2Y11-Mediated Signaling
Fruscione F, Scarfì S, Ferraris C, Bruzzone S, Benvenuto F, Guida L, Uccelli A, Salis A, Usai C, Jacchetti E, Ilengo C, Scaglione S, Quarto R, Zocchi E, De Flora A
Stem cells and development, 2011

In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis.
Milanese M, Zappettini S, Jacchetti E, Bonifacino T, Cervetto C, Usai C, Bonanno G.
Journal of neurochemistry, 2010

Gamma-amino butyric acid (GABA) release in the ciliated protozoon Paramecium occurs by neuronal-like exocytosis.
Ramoino P, Milanese M, Candiani S, Diaspro A, Fato M, Usai C, Bonanno G.
Journal of experimental biology, 2010

Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.
Bruzzone S, Basile G, Chothi MP, Nobbio L, Usai C, Jacchetti E, Schenone A, Guse AH, Di Virgilio F, De Flora A, Zocchi E.

Mechanisms of bradykinin-induced contraction in human fetal lung fibroblasts
Petecchia L., Sabatini F., Usai C., Carnevali S., Ognibene M., Vanni C., Eva A., Fabbri L.M., Rossi G.A., Ricciardolo F.L.

Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose.
Bodrato N, Franco L, Fresia C, Guida L, Usai C, Salis A, Moreschi I, Ferraris C, Verderio C, Basile G, Bruzzone S, Scarfì S, De Flora A, Zocchi E.

The Role of the C-Terminus for Functional Heteromerization of the Plant Channel KDC1
Naso A; Dreyer I; Pedemonte L; Testa I; Gomez-Porras JL; Usai C; Mueller-Rueber B; Diaspro A; Gambale F; Picco C
Biophysical journal (Print), 2009
DOI: 10.1016/j.bpj.2009.02.055

Glutamate release from astrocytic gliosomes under physiological and pathological conditions.
Milanese M, Bonifacino T, Zappettini S, Usai C, Tacchetti C, Nobile M, Bonanno G.
International review of neurobiology, 2009

P2X7-mediated Increased Intracellular Calcium Causes Functional Derangement in Schwann Cells from Rats with CMT1A Neuropathy.
Nobbio L, Sturla L, Fiorese F, Usai C, Basile G, Moreschi I, Benvenuto F, Zocchi E, De Flora A, Schenone A, Bruzzone S.

Bronchial airway epithelial cell damage following exposure to cigarette smoke includes disassembly of tight junction components mediated by the extracellular signal-regulated kinase 1/2 pathway.
Petecchia L, Sabatini F, Varesio L, Camoirano A, Usai C, Pezzolo A, Rossi GA.
Chest (Amer. Coll. Chest Phys.), 2009

Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD.
Di Stefano A, Caramori G, Gnemmi I, Contoli M, Bristot L, Capelli A, Ricciardolo FL, Magno F, D'Anna SE, Zanini A, Carbone M, Sabatini F, Usai C, Brun P, Chung KF, Barnes PJ, Papi A, Adcock I, Balbi B.
Thorax, 2009

Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis.
Magnone M, Bruzzone S, Guida L, Damonte G, Millo E, Scarfì S, Usai C, Sturla L, Palombo D, De Flora A, Zocchi E.

Biophysical effects of the natural product euplotin C on the Paramecium membrane
Ramoino P., F. Dini, P. Bianchini, A. Diaspro, G. Guella, C. Usai
Journal of computational biology, 2009

The Plant Hormone Abscisic Acid Stimulates The Proliferation Of Human Hemopoietic Progenitors Through The Second Messenger Cyclic ADP-Ribose.
Scarfì S, Fresia C, Ferraris C, Bruzzone S, Fruscione F, Usai C, Benvenuto F, Magnone M, Podestà M, Sturla L, Guida L, Albanesi E, Damonte G, Salis A, De Flora A, Zocchi E.
Stem cells (Dayt. Ohio), 2009

LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells.
Sturla L, Fresia C, Guida L, Bruzzone S, Scarfi' S, Usai C, Fruscione F, Magnone M, Millo E, Basile G, Grozio A, Jacchetti E, Allegretti M, De Flora A, Zocchi E.

NAADP(+) is an agonist of the human P2Y(11) purinergic receptor.
Moreschi I, Bruzzone S, Bodrato N, Usai C, Guida L, Nicholas RA, Kassack MU, Zocchi E, De Flora A.
Cell calcium (Edinburgh), 2008

Functional expression of release-regulating glycine transporters GLYT1 on GABAergic neurons and GLYT2 on astrocytes in mouse spinal cord.
Raiteri L, Stigliani S, Usai C, Diaspro A, Paluzzi S, Milanese M, Raiteri M, Bonanno G.
Neurochemistry international, 2008

Presynaptic mGlu1 and mGlu5 autoreceptors facilitate glutamate exocytosis from mouse cortical nerve endings.
Musante V, Neri E, Feligioni M, Puliti A, Pedrazzi M, Conti V, Usai C, Diaspro A, Ravazzolo R, Henley JM, Battaglia G, Pittaluga A.
Neuropharmacology, 2008

Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic-ADP ribose as second messenger.
Bruzzone S, Bodrato N, Usai C, Guida L, Moreschi I, Nano R, Antonioli B, Fruscione F, Magnone M, Scarfì S, De Flora A, Zocchi E.
The Journal of biological chemistry (Print), 2008

Cyclic ADP-Ribose-Mediated Expansion and Stimulation of Human Mesenchymal Stem Cells by the Plant Hormone Abscisic Acid.
Scarfì S, Ferraris C, Fruscione F, Fresia C, Guida L, Bruzzone S, Usai C, Parodi A, Millo E, Salis A, Burastero G, De Flora A, Zocchi E.
Stem cells (Dayt. Ohio), 2008

Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger.
Bruzzone S, Moreschi I, Usai C, Guida L, Damonte G, Salis A, Scarfì S, Millo E, De Flora A, Zocchi E.
Proceedings of the National Academy of Sciences of the United States of America, 2007

The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes.
Bonanno G, Raiteri L, Milanese M, Zappettini S, Melloni E, Pedrazzi M, Passalacqua M, Tacchetti C, Usai C, Sparatore B.
International review of neurobiology, 2007

Evidence for ciliary pigment localization in colored ciliates and implications for their photosensory transduction chain: A confocal microscopy study.
Colombetti G, Checcucci G, Lucia S, Usai C, Ramoino P, Bianchini P, Pesce M, Vicidomini G, Diaspro A.
Microscopy research and technique (Print), 2007
DOI: 10.1002/jemt.20508

Effect of the bioactive metabolite euplotin C on phagocytosis and fluid-phase endocytosis in the single-celled eukaryote Paramecium.
Ramoino P, Usai C, Maccione S, Beltrame F, Diaspro A, Fato M, Guella G, Dini F.
Aquatic toxicology, 2007

Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes.
Bruzzone S., Moreschi I., Guida L., Usai C., Zocchi E., De Flora A.
Biochemical journal (Lond., 1984), 2006

Endocytosis of GABAB receptors modulates membrane excitability in the single-celled organism Paramecium.
Ramoino P., Diaspro A., Beltrame F., Fato M., Gallus L., Usai C.
Journal of cell science, 2006

Glia re-sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate.
Stigliani S., Zappettini S., Raiteri L., Passalacqua M., Melloni E., Venturi C., Tacchetti C., Diaspro A., Usai C., Bonanno G.
Journal of neurochemistry, 2006

Co existence of GABA and Glu transporters in the central nervous system.
Bonanno G, Raiteri L, Paluzzi S, Zappettini S, Usai C, Raiteri M.
Current topics in medicinal chemistry (Print), 2006

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated activation of murine N9 microglial cell line.
Franco L., Bodrato N., Moreschi.I, Usai C., Bruzzone S., Scarfi S., Zocchi E., De Flora A.
Journal of neurochemistry, 2006

Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes.
Moreschi I, Bruzzone S, Nicholas RA, Fruscione F, Sturla L, Benvenuto F, Usai C, Meis S, Kassack MU, Zocchi E, De Flora A.

Multi-photon excitation microscopy.
Diaspro A., Bianchini P., Vicidomini P., Faretta M.,Ramoino P., Usai C.

ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells.
Basile G., Taglialatela-Scafati O., Damonte G., Armirotti A., Bruzzone S., Guida L., Franco L., Usai C., Fattorusso E., De Flora A., Zocchi E.
Proceedings of the National Academy of Sciences of the United States of America, 2005

A role for GABA(A) receptors in the modulation of Paramecium swimming behavior.
Bucci G., Ramoino P., Diaspro A., Usai C.
Neuroscience letters (Print), 2005

Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors.
Podesta M., Benvenuto F., Pitto A., Figari O., Bacigalupo A., Bruzzone S., Guida L., Franco L., Paleari L., Bodrato N., Usai C., De Flora A., Zocchi E.

Activation of gamma-aminobutyric acid GAT-1 transporters on glutamatergic terminals of mouse spinal cord mediates glutamate release through anion channels and by transporter reversal.
Raiteri L., Stigliani S., Patti L., Usai C., Bucci G., Diaspro A., Raiteri M., Bonanno G.
Journal of neuroscience research, 2005

GABAB receptor intracellular trafficking after internalization in Paramecium.
Paola Ramoino; Cesare Usai; Francesco Beltrame; Marco Fato; Lorenzo Gallus; Grazia Tagliafierro; Raffaella Magrassi; Alberto Diaspro
Microscopy research and technique (Print), 2005
DOI: 10.1002/jemt.20250

GABAA receptor subunits identified in Paramecium by immunofluorescence confocal microscopy.
Ramoino P., Scaglione S., Diaspro A., Beltrame F., Fato M., Usai C.
FEMS microbiology letters, 2004

ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells.
Bruzzone S., De Flora A., Usai C., Graeff R., Lee H.C.
Biochemical journal (Lond., 1984), 2003

Patch-clamp recordings in isolated sponge (Axinella polypoides) cells.
Carpaneto A., Magrassi R., Zocchi E., Cerrano C., Usai C.
Journal of biochemical and biophysical methods, 2003
DOI: 10.1016/S0165-022X(02)00184-7

Swimming behavior regulation by GABAB receptors in Paramecium.
Ramoino P., Fronte P., Beltrame F., Diaspro A., Fato M., Raiteri L., Stigliani S., Usai C.
Experimental cell research, 2003

ABA- and cADPR-mediated effects on respiration and filtration downstream of the temperature-signaling cascade in sponges.
Zocchi E., Basile G., Cerrano C., Bavestrello G., Giovine M., Bruzzone S., Guida L., Carpaneto A., Magrassi R., Usai C.:
Journal of cell science, 2003

Paracrinally stimulated expansion of early human hemopoietic progenitors by stroma-generated cyclic ADP-ribose.
Zocchi E. 1, Podestà M. 2, Pitto A. 2, Usai C. 3, Bruzzone S. 1, Franco L. 4, Guida L. 1, Bacigalupo A. 2, De Flora A. 1

The temperature-signaling cascade in sponges involves a heat-gated cation channel, abscisic acid, and cyclic ADP-ribose
Zocchi E, Carpaneto A, Cerrano C, Bavestrello G, Giovine M, Bruzzone S, Guida L, Franco L, Usai C
Proceedings of the National Academy of Sciences of the United States of America, 2001
DOI: 10.1073/pnas.261448698

Expression of CD38 Increases Intracellular Calcium Concentration and Reduces Doubling Time in HeLa and 3T3 Cells
Zocchi E., Daga A., Usai C., Franco L., Guida L., Bruzzone S., Costa A., Marchetti C., De Flora A
The Journal of biological chemistry (Print), 1998
DOI: 10.1074/jbc.273.14.8017

Ectocellular in vitro and in vivo metabolism of cADP-ribose in cerebellum
De Flora A, Guida L, Franco L, Zocchi E, Pestarino M, Usai C, Marchetti C, Fedele E, Fontana G, Raiteri M
Biochemical journal (Lond., 1984), 1996

High affinity block by nimodipine of the internal calcium elevation in chronically depolarized rat cerebellar granule neurons
Marchetti C., Usai C.
Neuroscience letters (Print), 1996
DOI: 10.1016/0304-3940(96)12492-7

Amico C; Marchetti C; Nobile M; Usai C
The Journal of neuroscience, 1995

Functional characterization of the effect of nimodipine on the calcium current in rat cerebellar granule cells
Marchetti C; Amico C; Usai C
Journal of neurophysiology, 1995

Effect of gangliosides on phospholipid bilayers: a study with the lipophilic ions relaxation method
Usai C, Robello M, Gambale F, Marchetti C
The journal of membrane biology (Print), 1984
DOI: 10.1007/BF01870728

GM1 micelles modify the transport properties of the ionophore gramicidin D in artificial planar bilayers
Gambale F, Marchetti C, Usai C, Robello M, Gorio A
Journal of neuroscience research, 1984
DOI: 10.1002/jnr.490120222

Capacitance--voltage relationship in phospholipid bilayers containing gangliosides
Usai C, Marchetti C, Gambale F, Robello M, Gorio A
FEBS letters (Print), 1983

Properties of ionic transport through phospholipid-glycolipid artificial bilayers
Gambale F, Robello M, Usai C, Marchetti C
Biochimica et biophysica acta (Print), 1982