Angelo Di Garbo

Research staff

*Personal details Name: Angelo Surname: Di Garbo Affiliation: Italian National Research Council (CNR) - Institute of Biophysics, via G. Moruzzi n.1, 56127 Pisa, Italy *Positions and Education 1991: Master's degree in Physics, Department of Physics, University of Pisa, Italy. 1995: PhD in General Physics, Department of Physics, University of Pisa, Italy. 1998: Postdoctoral fellowship, Department of Physics, University of Trento, Italy. 2001-present: Researcher (permanent position). *Research interests: Nonlinear Dynamics, Complex System and Nonlinear Evolution Equations. *Teaching Nonlinear Dynamics, Department of Physics, University of Pisa Biophysical Modelling of Complex Systems, Department of Biomedical Engineering, University of Pisa

orcid://0000-0002-3314-4751,

Contact:

- Email angelo.digarbo@ibf.cnr.it
- Phone +39-050-3152577
- Location Pisa

Website:

http://www.pi.ibf.cnr.it/?page_id=1537

Research interests:

- Nonlinear Dynamics (Principal investigator)
- Nonlinear Time Series Analysis (Principal investigator)
- Mathematical Modeling of Biological Systems (Principal investigator)

Further collaborations:

- Dr. Riccardo Meucci (CNR - INO, Firenze)
- Dr. Matteo Caleo (CNR - IN, Pisa)
- Dr. Stefano Galatolo (Dep. of Mathematics, Pisa)

Financial support:

- Stabilità e instabilità in sistemi con rumore, un approccio computer assistito. Istituto nazionale di alta matematica (gruppo GNAMPA).
- Characterizing the Biophysical Properties of Functional Networks of Neurons. Cnr Short-Term mobility (a favore del Prof. H.D.I. Abarbanel) per una sua permanenza presso l’Istituto di Biofisica del Cnr.
- Transferring Information from Data to Model. Cnr Short-Term mobility (a favore del Dott. Fabio Vallone) per una sua permanenza presso il Biocircuits Institute (University Of California San Diego).
- Analisi nonlineare di segnali di modelli animali di ischemia (ictus). Fondazione Caripisa.

Key publications:

C. Alia, C. Spalletti, S. Lai, A. Panarese, G. Lamola, F. Bertolucci, F. Vallone, A. Di Garbo, C. Chisari, S. Micera, M. Caleo, Neuroplastic changes following brain ischemia and their contribution to stroke recovery: novel approaches in neurorehabilitation. Front. Cell. Neurosci., doi.org/10.3389/fncel.2017.00076 (2017).

F. Vallone, A. Cintio, S. Chillemi, A. Di Garbo, Thalamic inputs modulate cortical activity: Possibility to control the generation and the termination of seizure-like behavior, Neurocomputing, vol. 151, 34-58 (2015).

J-M. Ginoux, B. Muthuswamy, R. Meucci, S. Euzzor, A. Di Garbo, K. Ganesan, A physical memristor based Muthuswamy–Chua–Ginoux system. Scientific Reports, vol. 10, 19206 DOI: https://doi.org/10.1038/s41598-020-76108-z (2020).

Marangio, L.; Sedro, J.; Galatolo, S.; Di Garbo, A.; Ghil, M., Arnold Maps with Noise: Differentiability and Non-monotonicity of the Rotation Number. Journal of Statistical Physics, vol. 179, p. 1594–1624 DOI: https://doi.org/10.1007/s10955-019-02421-1 (2020) .

A. Di Garbo, Anharmonic Longitudinal Motion of Bases and Dynamics of Nonlinear Excitation in DNA. Biophysical Chemistry, vol. 208, 76-83 (2015).

Publications (49):

A Fast Method for Detecting Interdependence between Time Series and Its Directionality
Paolini, Gabriele and Sarnari, Francesco and Meucci, Riccardo and Euzzor, Stefano and Ginoux, Jean-Mark and Chillemi, Santi and Fronzoni, Leone and Arecchi, Fortunato Tito and Di Garbo, Angelo
international journal of bifurcation and chaos in applied sciences and engineeringissn: 0218-1274world scientific., 31, 2021
DOI: 10.1142/S0218127421502394

On the destabilization of a periodically driven three-dimensional torus
Euzzor S.; Di Garbo A.; Ginoux J.-M.; Zambrano S.; Arecchi F.T.; Meucci R.
nonlinear dynamics (dordr., online)issn: 1573-269xkluwer, 103, 2021
DOI: 10.1007/s11071-020-06174-5

A physical memristor based Muthuswamy–Chua–Ginoux system
Jean-Marc Ginoux, Bharathwaj Muthuswamy, Riccardo Meucci, Stefano Euzzor, Angelo Di Garbo, Kaliyaperumal Ganesan
Scientific Reports, 10, 2020
DOI: 10.1038/s41598-020-76108-z

Implementing Poincaré Sections for a Chaotic Relaxation Oscillator
S. Euzzor; A. Di Garbo; J.-M. Ginoux; F. T. Arecchi; R. Meucci
IEEE Transactions on Circuits and Systems II: Express Briefs, 67, 2020
DOI: 10.1109/TCSII.2019.2924475

Arnold Maps with Noise: Differentiability and Non-monotonicity of the Rotation Number
Marangio L, Sedro J, Galatolo S, Di Garbo A, Ghil M
Journal of statistical physics, 179, 2019
DOI: 10.1007/s10955-019-02421-1

Delayed dynamics in an electronic relaxation oscillator
Di Garbo A, Euzzor S, Ginoux JM, Arecchi FT, Meucci R
Physical Review E, 100, 2019
DOI: 10.1103/PhysRevE.100.032224

Implementing Poincare' Sections for a Chaotic Relaxation Oscillator
Euzzor S, Di Garbo A, Ginoux JM, Arecchi FT, Meucci R
IEEE Transactions on Circuits and Systems II: Express Briefs, 67, 2019
DOI: 10.1109/TCSII.2019.2924475

Phase-locking patterns in a resonate and fire neural model with periodic drive
Marangio L, Galatolo S, Fronzoni L, Chillemi S, Di Garbo A
Biosystems, 184, 2019
DOI: 10.1016/j.biosystems.2019.103992

Torus Breakdown in a Uni Junction Memristor
Cinoux JM, Meucci R, Euzzor S, di Garbo A
International journal of bifurcation and chaos in applied sciences and engineering, 28, 2018
DOI: 10.1142/S0218127418501286

Dynamical properties of LFPs from mice with unilateral injection of TeNT
Vannini E.; Caleo M.; Chillemi S.; Di Garbo A.
Biosystems, 161, 2017
DOI: 10.1016/j.biosystems.2017.09.009

Neuroplastic changes following brain ischemia and their contribution to stroke recovery: Novel approaches in neurorehabilitation
Alia C.; Spalletti C.; Lai S.; Panarese A.; Lamola G.; Bertolucci F.; Vallone F.; Di Garbo A.; Chisari C.; Micera S.; Caleo M.
Frontiers in cellular neuroscience, 11, 2017
DOI: 10.3389/fncel.2017.00076

Anharmonic longitudinal motion of bases and dynamics of nonlinear excitation in DNA
Di Garbo A.
Biophysical chemistry, 208, 2016
DOI: 10.1016/j.bpc.2015.09.006

Post-stroke longitudinal alterations of inter-hemispheric correlation and hemispheric dominance in mouse pre-motor cortex
Vallone F.; Lai S.; Spalletti C.; Panarese A.; Alia C.; Micera S.; Caleo M.; Di Garbo A.
PloS one, 11, 2016
DOI: 10.1371/journal.pone.0146858

Time evolution of interhemispheric coupling in a model of focal neocortical epilepsy in mice
Vallone F.; Vannini E.; Cintio A.; Caleo M.; Di Garbo A.
Physical review. E, Statistical, nonlinear and soft matter physics, 94, 2016
DOI: 10.1103/PhysRevE.94.032409

Existence of anticorrelations for local field potentials recorded from mice reared in standard condition and environmental enrichment
F. Vallone, A. Cintio, M. Mainardi, M. Caleo, and A. Di Garbo
Physical review. E, Statistical, nonlinear and soft matter physics , 91, 2015
DOI: 10.1103/PhysRevE.91.012702

Thalamic inputs modulate cortical activity: Possibility to control the generation and the termination of seizure-like behaviour
Vallone, Fabio; Cintio, Andrea; Chillemi, Santi; Di Garbo, Angelo
Neurocomputing , 151, 2015
DOI: 10.1016/j.neucom.2014.09.070

Environmental enrichment strengthens corticocortical interactions and reduces amyloid-beta oligomers in aged mice
Mainardi, Marco; Di Garbo, Angelo; Caleo, Matteo; Berardi, Nicoletta; Sale, Alessandro; Maffei, Lamberto
Frontiers in aging neuroscience, 6, 2014
DOI: 10.3389/fnagi.2014.00001

Longitudinal displacements of base pairs in DNA and effects on the dynamics of nonlinear excitations
Di Garbo A
Mathematical biosciences, 245, 2013
DOI: 10.1016/j.mbs.2013.03.010

The role of glutamatercic and GABAergic synapses on the dynamics of neural networks: How they impact the transition to seizure?
Di Garbo A, Barbi M, Chillemi S
Neurocomputing, 114, 2013
DOI: 10.1016/j.neucom.2012.08.045

P2X7 receptor-mediated calcium dynamics in HEK293 cells: experimental characterization and modelling approach
Di Garbo A; Alloisio S; Nobile M
Physical biology, 9, 2012
DOI: 10.1088/1478-3975/9/2/026001

A network of pyramidal neurons is sensitive to the timing of its excitatory inputs
Chillemi S, Barbi M, Di Garbo A
Neurocomputing, 74, 2011

Environmental enrichment modulates cortico-cortical interactions in the mouse
Di Garbo A, Mainardi M, Chillemi S, Maffei L, Caleo M
Plos one, 6, 2011
DOI: 10.1371/journal.pone.0025285

Evidence for two conductive pathways in P2X(7) receptor: differences in modulation and selectivity.
Alloisio S, Di Garbo A, Barbieri R, Bozzo L, Ferroni S, Nobile M
Journal of neurochemistry, 113, 2010

Evidence for two conductive pathways in P2X7 receptor: differences in modulation and selectivity.
Alloisio, S; Di Garbo, A; Barbieri, R; Bozzo, L; Ferroni, S; Nobile, M
JOURNAL OF NEUROCHEMISTRY, 113, 2010
DOI: 10.1111/j.1471-4159.2010.06649.x

Variable renewal rate and growth properties of cell populations in colon crypts.
Di Garbo A, Johnston MD, Chapman SJ, Maini PK
Physical review e, 81, 2010
DOI: 10.1103/PhysRevE.81.061909

A Network of coupled pyramidal neurons behaves as a coincidence detector
Chillemi S, Barbi M, Di Garbo A
Lecture notes in computer science, 5601, 2009

Dynamics of a minimal neural model consisting of an astrocyte, a neuron, and an interneuron
Di Garbo A
Journal of biological physics, 35, 2009
DOI: 10.1007/s10867-009-9143-2

Temporal information coding properties of a network of inhibitory interneurons
Di Garbo A
Cognitive processing, 10, 2009
DOI: 10.1007/s10339-008-0228-9

Botulinum neurotoxin E (BoNT/E) reduces CA1 neuron loss and granule cell dispersion, with no effects on chronic seizures, in a mause model of temporal lobe epilepsy.
Antonucci F.;Di Garbo A.; Novelli E.; Manno I.; Sartucci F.; Bozzi Y.; Caleo M.
Experimental neurology, 210, 2008
DOI: 10.1016/j.expneurol.2007.11.012

The electrical coupling confers to a network of interneurons the ability of transmitting excitatory inputs with high temporal precision
Di Garbo Angelo
Brain research, 1225, 2008
DOI: 10.1016/j.brainres.2008.05.021

Calcium signalling in astrocytes and modulation of neuronal activity
Di Garbo A; Barbi M; Chillemi S; Alloisio S; Nobile M
Biosystems, 89, 2007
DOI: 10.1016/j.biosystems.2006.05.013

Coincidence detector properties of small networks of interneurons
Di Garbo A; Barbi M; Chillemi S
Lecture notes in computer science, 4729, 2007

Improved Integrate-and-Fire model for RSA
Barbi M.; A. Di Garbo; R. Balocchi
Mathematical biosciences and engineering, 4, 2007
DOI: 10.3934/mbe.2007.4.609

Stochastic resonance in two simple compare-and-fire models
Barbi M; Di Garbo A.; Barbi F.
Biosystems, 89, 2007
DOI: 10.1016/j.biosystems.2006.05.011

The kinetics of the IPSC, the heterogeneity and the noise affect the firing coherence of a population of inhibitory interneurons
Di Garbo A; Panarese A; Barbi M; Chillemi S
Neurocomputing, 70, 2007
DOI: 10.1016/j.neucom.2006.05.021

The synchronization properties of a network of inhibitory interneurons depend on the biophysical model.
Di Garbo A.; M. Barbi; S. Chillemi
Biosystems, 88, 2007
DOI: 10.1016/j.biosystems.2006.08.011

A minimal model for the respiratory sinus arrhythmia
Barbi M; Chillemi S; Di Garbo A; Balocchi R; Menicucci D
Biological cybernetics, 94, 2006
DOI: 10.1007/s00422-005-0043-7

Signal processing properties of fast spiking interneurons
Di Garbo A; Barbi M; Chillemi S
Biosystems , 86, 2006
DOI: 10.1016/j.biosystems.2006.03.009

Gap Junctions promote synchronous activities in a network of inhibitory interneurons.
Di Garbo, A; Panarese, A; Chillemi, S
BIOSYSTEMS, 79, 2005
DOI: 10.1016/j.biosystems.2004.09.004

Gap-junctions promote synchrony in a network of inhibitory interneurons in the presence of heterogeneities and noise
Chillemi, S; Panarese, A; Barbi, M; Di Garbo, A

Relationship of non-protein thiol pools and accumulated Cd or Hg in the marine macrophyte Posidonia oceanica (L.) Delile
Maserti, Be; Ferrillo, V; Avdis, O; Nesti, U; Di Garbo, A; Catsiki, A; Maestrini, P L
AQUATIC TOXICOLOGY, 75, 2005
DOI: 10.1016/j.aquatox.2005.08.008

Signal Transmission and Synchrony Detection in a Network of Inhibitory Interneurons
Di Garbo, A; Panarese, A; Barbi, M; Chillemi, S

The after-hyperpolarization amplitude and the rise time constant of IPSC affect the synchronization properties of networks of inhibitory interneurons
Di Garbo, A; Panarese, A; Barbi, M; Chillemi, S

Phase locking states between fast-spiking interneurons coupled by electrical and chemical synapses
DI GARBO, Angelo; Panarese, Alessandro; Chillemi, Santi
NEUROCOMPUTING, 2004
DOI: 10.1016/j.neucom.2004.01.037

Homoclinic chaos in a laser: synchronization and its implications in biological systems
Arecchi, Ft; Meucci, R; Di Garbo, A; Allaria, E
OPTICS AND LASERS IN ENGINEERING, 39, 2003

Stochastic resonance in a sinusoidally forced LIFmodel with noisy threshold.
Barbi, M; Chillemi, S; Di Garbo, A; Reale, L
BIOSYSTEMS, 71, 2003

Synchronous firing in a population of inhibitory interneurons coupled by electrical and chemical synapses
Chillemi, S; Di Garbo, A; Panarese, A

Synchronization of homoclinic chaos
Allaria, E; Arecchi, Ft; Di Garbo, A; Meucci, R
PHYSICAL REVIEW LETTERS (PRINT), 86, 2001

Heart rate and blood pressure response to short-term head-down bed rest: A nonlinear approach
Balocchi, Rita; Di Garbo, Angelo; Michelassi, Claudio; Chillemi, Santi; Varanini, Maurizio; Barbi, Michele; Legramante, Jacopo Maria; Raimondi, Gianfranco F.; Zbilut, Joseph P.
METHODS OF INFORMATION IN MEDICINE, 39, 2000