Puglisi Rita, Cioni Patrizia, Gabellieri Edi, Presciuttini Gianluca, Pastore Annalisa and Temussi Piero Andrea
Biophysical journal (Print), 2022
DOI: 10.1016/j.bpj.2022.03.010
Use of Exogenous in Human Therapy: Approved Drugs and Potential Applications
Cioni Patrizia, Gabellieri Edi, Campanini Barbara, Bettati Stefano and Raboni Samanta
Current medicinal chemistry, 2022
DOI: 10.2174/0929867328666210713094722
Interplay between extracellular polymeric substances (EPS) from a marine diatom and model nanoplastic through eco-corona formation
Grassi Giacomo; Gabellieri Edi; Cioni Patrizia; Paccagnini Eugenio; Faleri Claudia; Lupetti Pietro; Corsi Ilaria and Morelli Elisabetta
Science of the total environment, 2020
DOI: 10.1016/j.scitotenv.2020.138457
Soluble and Nanoporous Silica Gel-Entrapped C-freundii Methionine gamma-Lyase
Morozova EA, Kulikova VV, Faggiano S, Raboni S, Gabellieri E, Cioni P, Anufrieva NV, Revtovich SV, Demidkina T, Mozzarelli A
Journal of nanoscience and nanotechnology (Print), 2018
DOI: 10.1166/jnn.2018.14333
Engineering methionine ?-lyase from Citrobacter freundii for anticancer activity
Raboni S, Revtovich S, Demitri N, Giabbai B, Storici P, Cocconcelli C, Faggiano S, Rosini E, Pollegioni L, Galati S, Buschini A, Morozova E, Kulikova V, Nikulin A, Gabellieri E, Cioni P, Demidkina T, Mozzarelli A
Biochimica et biophysica acta. Proteins and proteomics, 2018
DOI: 10.1016/j.bbapap.2018.09.011
Gene cloning, characterization, and cytotoxic activity of methionine ?-lyase from Clostridium novyi
Kulikova, V.V. and Morozova, E.A. and Revtovich, S.V. and Kotlov, M.I. and Anufrieva, N.V. and Bazhulina, N.P. and Raboni, S. and Faggiano, S. and Gabellieri, E. and Cioni, P. and Belyi, Y.F. and Mozzarelli, A. and Demidkina, T.V.
IUBMB life (Print), 2017
DOI: 10.1002/iub.1649
Temperature and pressure effects on GFP mutants: Explaining spectral changes by molecular dynamics simulations and TD-DFT calculations
Jacchetti E.; Gabellieri E.; Cioni P.; Bizzarri R.; Nifosi R.
PCCP. Physical chemistry chemical physics (Print), 2016
DOI: 10.1039/c6cp01274d
The response of Phaeodactylum tricornutum to quantum dot exposure: Acclimation and changes in protein expression.
Morelli E., Salvadori E., Basso B., Tognotti D., Cioni P., Gabellieri E.
Marine environmental research, 2015
DOI: 10.1016/j.marenvres.2015.06.018
A SELDI-TOF approach to ecotoxicology: Comparative profiling of low molecular weight proteins from a marine diatom exposed to CdSe/ZnS quantum dots
Scebba F.; Tognotti D.; Presciuttini G.; Gabellieri E.; Cioni P.; Angeloni D.; Basso B.; Morelli E.
Ecotoxicology and environmental safety (Online), 2015
DOI: 10.1016/j.ecoenv.2015.08.024
Temperature and pressure effects on C112S azurin: Volume, expansivity, and flexibility changes
Cioni P.; Gabellieri E.; Marchal S.; Lange R.
Proteins (Online), 2014
DOI: 10.1002/prot.24532
Interaction of CdSe/ZnS quantum dots with the marine diatom Phaeodactylum tricornutum and the green alga Dunaliella tertiolecta: A biophysical approach
Morelli E, Salvadori E, Bizzarri R, Cioni P, Gabellieri E
Biophysical chemistry (Print), 2013
DOI: 10.1016/j.bpc.2013.06.007
Temperature and pressure dependence of azurin stability as monitored by tryptophan fluorescence and phosphorescence. The case of F29A mutant
Tognotti D, Gabellieri E, Morelli E, Cioni P
Biophysical chemistry (Print), 2013
DOI: 10.1016/j.bpc.2013.06.005
Chemical stability of CdSe quantum dots in seawater and their effects on a marine microalga
Morelli E; Cioni P; Posarelli M; Gabellieri E
Aquatic toxicology, 2012
DOI: 10.1016/j.aquatox.2012.06.012
Protein dynamics and pressure: what can high pressure tell us about protein structural flexibility?
Cioni P, Gabellieri E
Biochimica et biophysica acta. Proteins and proteomics, 2011
DOI: 10.1016/j.bbapap.2010.09.017
Does azurin bind to the transactivation domain of p53? A Trp phosphorescence study
Gabellieri E, Bucciantini M, Stefani M, Cioni P
Biophysical chemistry (Print), 2011
Protein structural changes induced by glutathione-coated CdS quantum dots as revealed by Trp phosphorescence
Gabellieri E, Cioni P, Balestreri E, Morelli E
European biophysics journal, 2011
DOI: 10.1007/s00249-011-0736-x
Cavity-Creating Mutations in Pseudomonas aeruginosa Azurin: Effects on Protein Dynamics and Stability.
Gabellieri E, Balestreri E, Galli A., and P Cioni.
Biophysical journal (Print), 2008
Role of protein cavities on unfolding volume change and on internal dynamics under pressure.
Cioni P.
Biophysical journal (Print), 2006
Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surface.
Maragliano L, Falconi M, Sergi A, Cioni P, Castelli S, Lania A, Stroppolo ME, Strambini G, Ferrario M, Desideri A.
Biophysical journal (Print), 2005
Effects of sucrose on the internal dynamics of azurin.
Cioni P., Bramanti E., Strambini G.B.
Biophysical journal (Print), 2005
Effects of cavity-forming mutations on the internal dynamics of azurin
Patrizia Cioni, Ellen de Waal,y Gerard W. Canters,y and Giovanni B. Strambini
Biophysical journal (Print), 2004
Active-site copper and zinc ions modulate the quaternari structure of prokaryotic Cu, Zn superoxide dismutase
Cioni P., Pesce A., Della Rocca B.M., Castelli S., Falconi M., Parrilli L., Bolognesi M., Strambini G., Desideri A.
Journal of Molecular Biology, 2003
Effect of heavy water on protein flexibility
Cioni, P; Strambini, GB
Biophysical journal (Print), 2002
DOI: 10.1016/j.bpc.2011.07.008
Tryptophan phosphorescence and pressure effects on protein structure
Cioni P. 1, Strambini G.B. 1
Effect of heavy water on protein flexibility
Patrizia Cioni and Giovanni B. Strambini
Biophysical journal (Online), 2002
Alteration of the intramolecular dynamics of glycogen phosphorylase b by allosteric ligands
Szarka, Á.b and Gabellieri, E.c and Gonnelli, M.c and Cioni, P.c and Lakos, Z.a and Somogyi, B.a
Journal of photochemistry and photobiology. B, Biology (Print), 1998
DOI: 10.1016/S1011-1344(97)00119-X
PRESSURE EFFECTS ON PROTEIN FLEXIBILITY MONOMERIC PROTEINS
CIONI, P; STRAMBINI, GB
Journal of Molecular Biology, 1994
DOI: 10.1006/jmbi.1994.1579
Heterogeneity of protein conformation in solution from the lifetime of tryptophan phosphorescence
Cioni, P. and Gabellieri, E. and Gonnelli, M. and Strambini, G.B.
Biophysical chemistry (Print), 1994
CHARACTERIZATION OF TRYPTOPHAN PHOSPHORESCENCE OF ASPARTATE-AMINOTRANSFERASE FROM ESCHERICHIA-COLI
CIONI, P; ONUFFER, JJ; STRAMBINI, GB
European journal of biochemistry (Print), 1992
DOI: 10.1111/j.1432-1033.1992.tb17345.x
Relationship of disulfide bonds to the maintenance of the active secondary structure of alfalfa (Medicago sativa ) leaves protease inhibitor
Gonnelli, M. and Balestreri, E. and Romagnoli, A. and Fissi, A. and Cioni, P. and Gabellieri, E. and Felicioli, R.
Journal of agricultural and food chemistry, 1986
Purification and characterization of two leaf polypeptide inhibitors of leaf protease from alfalfa (Medicago sativa)
Gonnelli, M.a and Cioni, P.a and Romagnoli, A.a and Gabellieri, E.a and Balestreri, E.a and Felicioli, R.b
Archives of biochemistry and biophysics (Print), 1985
Patrizia Cioni
Degree in Biological Science, University of Pisa (1982); PhD in Biochemistry, University of Pisa (1988); Post doctoral fellowship Department of Biochemistry, Univ. of Berkeley, San Francisco, USA (1988-1990); Post doctoral fellowship Max Planck Institute fur Biophysikalische Chemie, Gottingen, Germany (1996)
orcid://0000-0002-2243-6716,
Research interests:
- Trp phosphorescence spectroscopy applied to the study of protein structure and dynamics. (Principal investigator)
Key publications:
Morozova EA, Kulikova VV, Faggiano S, Raboni S, Gabellieri E, Cioni P, Anufrieva NV, Revtovich SV, Demidkina TV, Mozzarelli A (2018). Soluble and nanoporous silica gel-entrapped C.freundii methionine gamma-lyase. Journal of Nanoscience and Nanotechnology 18:2210-2219
Kulikova VV, Morozova EA, Revtovich SV, Kotlov MI, Anufrieva NV, Bazhulina NP, Raboni S, Faggiano S, Gabellieri E, Cioni P, Belyi YF, Mozzarelli A, Demidkina TV (2017). Gene cloning, characterization and cytotoxic activity of methionine gamma-lyase from Clostridium novyi. IUBMB Life 69:668-676
Jacchetti E, Gabellieri E, Cioni P, Bizzarri R, Nifosì R (2016). Temperature and pressure effects on GFP mutants: explaining spectral changes by molecular dynamics simulation and TD-DFT calculations. Physical Chemistry Chemical Physics 18:12828-12838
Cioni P, Gabellieri E, Marchal S, Lange R (2014). Temperature and pressure effects on C112S azurin: Volume, expansivity, and flexibility changes. Proteins 82:1787–1798
Cioni P, Gabellieri E (2011). Protein dynamics and pressure: what can high pressure tell us about protein structural flexibility? Biochim. Biophys. Acta 1814:934-941
Publications (31):
Heat and cold denaturation of yeast frataxin: The effect of pressurePuglisi Rita, Cioni Patrizia, Gabellieri Edi, Presciuttini Gianluca, Pastore Annalisa and Temussi Piero Andrea
Biophysical journal (Print), 2022
DOI: 10.1016/j.bpj.2022.03.010
Use of Exogenous in Human Therapy: Approved Drugs and Potential Applications
Cioni Patrizia, Gabellieri Edi, Campanini Barbara, Bettati Stefano and Raboni Samanta
Current medicinal chemistry, 2022
DOI: 10.2174/0929867328666210713094722
Interplay between extracellular polymeric substances (EPS) from a marine diatom and model nanoplastic through eco-corona formation
Grassi Giacomo; Gabellieri Edi; Cioni Patrizia; Paccagnini Eugenio; Faleri Claudia; Lupetti Pietro; Corsi Ilaria and Morelli Elisabetta
Science of the total environment, 2020
DOI: 10.1016/j.scitotenv.2020.138457
Soluble and Nanoporous Silica Gel-Entrapped C-freundii Methionine gamma-Lyase
Morozova EA, Kulikova VV, Faggiano S, Raboni S, Gabellieri E, Cioni P, Anufrieva NV, Revtovich SV, Demidkina T, Mozzarelli A
Journal of nanoscience and nanotechnology (Print), 2018
DOI: 10.1166/jnn.2018.14333
Engineering methionine ?-lyase from Citrobacter freundii for anticancer activity
Raboni S, Revtovich S, Demitri N, Giabbai B, Storici P, Cocconcelli C, Faggiano S, Rosini E, Pollegioni L, Galati S, Buschini A, Morozova E, Kulikova V, Nikulin A, Gabellieri E, Cioni P, Demidkina T, Mozzarelli A
Biochimica et biophysica acta. Proteins and proteomics, 2018
DOI: 10.1016/j.bbapap.2018.09.011
Gene cloning, characterization, and cytotoxic activity of methionine ?-lyase from Clostridium novyi
Kulikova, V.V. and Morozova, E.A. and Revtovich, S.V. and Kotlov, M.I. and Anufrieva, N.V. and Bazhulina, N.P. and Raboni, S. and Faggiano, S. and Gabellieri, E. and Cioni, P. and Belyi, Y.F. and Mozzarelli, A. and Demidkina, T.V.
IUBMB life (Print), 2017
DOI: 10.1002/iub.1649
Temperature and pressure effects on GFP mutants: Explaining spectral changes by molecular dynamics simulations and TD-DFT calculations
Jacchetti E.; Gabellieri E.; Cioni P.; Bizzarri R.; Nifosi R.
PCCP. Physical chemistry chemical physics (Print), 2016
DOI: 10.1039/c6cp01274d
The response of Phaeodactylum tricornutum to quantum dot exposure: Acclimation and changes in protein expression.
Morelli E., Salvadori E., Basso B., Tognotti D., Cioni P., Gabellieri E.
Marine environmental research, 2015
DOI: 10.1016/j.marenvres.2015.06.018
A SELDI-TOF approach to ecotoxicology: Comparative profiling of low molecular weight proteins from a marine diatom exposed to CdSe/ZnS quantum dots
Scebba F.; Tognotti D.; Presciuttini G.; Gabellieri E.; Cioni P.; Angeloni D.; Basso B.; Morelli E.
Ecotoxicology and environmental safety (Online), 2015
DOI: 10.1016/j.ecoenv.2015.08.024
Temperature and pressure effects on C112S azurin: Volume, expansivity, and flexibility changes
Cioni P.; Gabellieri E.; Marchal S.; Lange R.
Proteins (Online), 2014
DOI: 10.1002/prot.24532
Interaction of CdSe/ZnS quantum dots with the marine diatom Phaeodactylum tricornutum and the green alga Dunaliella tertiolecta: A biophysical approach
Morelli E, Salvadori E, Bizzarri R, Cioni P, Gabellieri E
Biophysical chemistry (Print), 2013
DOI: 10.1016/j.bpc.2013.06.007
Temperature and pressure dependence of azurin stability as monitored by tryptophan fluorescence and phosphorescence. The case of F29A mutant
Tognotti D, Gabellieri E, Morelli E, Cioni P
Biophysical chemistry (Print), 2013
DOI: 10.1016/j.bpc.2013.06.005
Chemical stability of CdSe quantum dots in seawater and their effects on a marine microalga
Morelli E; Cioni P; Posarelli M; Gabellieri E
Aquatic toxicology, 2012
DOI: 10.1016/j.aquatox.2012.06.012
Protein dynamics and pressure: what can high pressure tell us about protein structural flexibility?
Cioni P, Gabellieri E
Biochimica et biophysica acta. Proteins and proteomics, 2011
DOI: 10.1016/j.bbapap.2010.09.017
Does azurin bind to the transactivation domain of p53? A Trp phosphorescence study
Gabellieri E, Bucciantini M, Stefani M, Cioni P
Biophysical chemistry (Print), 2011
Protein structural changes induced by glutathione-coated CdS quantum dots as revealed by Trp phosphorescence
Gabellieri E, Cioni P, Balestreri E, Morelli E
European biophysics journal, 2011
DOI: 10.1007/s00249-011-0736-x
Cavity-Creating Mutations in Pseudomonas aeruginosa Azurin: Effects on Protein Dynamics and Stability.
Gabellieri E, Balestreri E, Galli A., and P Cioni.
Biophysical journal (Print), 2008
Role of protein cavities on unfolding volume change and on internal dynamics under pressure.
Cioni P.
Biophysical journal (Print), 2006
Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surface.
Maragliano L, Falconi M, Sergi A, Cioni P, Castelli S, Lania A, Stroppolo ME, Strambini G, Ferrario M, Desideri A.
Biophysical journal (Print), 2005
Effects of sucrose on the internal dynamics of azurin.
Cioni P., Bramanti E., Strambini G.B.
Biophysical journal (Print), 2005
Effects of cavity-forming mutations on the internal dynamics of azurin
Patrizia Cioni, Ellen de Waal,y Gerard W. Canters,y and Giovanni B. Strambini
Biophysical journal (Print), 2004
Active-site copper and zinc ions modulate the quaternari structure of prokaryotic Cu, Zn superoxide dismutase
Cioni P., Pesce A., Della Rocca B.M., Castelli S., Falconi M., Parrilli L., Bolognesi M., Strambini G., Desideri A.
Journal of Molecular Biology, 2003
Effect of heavy water on protein flexibility
Cioni, P; Strambini, GB
Biophysical journal (Print), 2002
DOI: 10.1016/j.bpc.2011.07.008
Tryptophan phosphorescence and pressure effects on protein structure
Cioni P. 1, Strambini G.B. 1
Effect of heavy water on protein flexibility
Patrizia Cioni and Giovanni B. Strambini
Biophysical journal (Online), 2002
Alteration of the intramolecular dynamics of glycogen phosphorylase b by allosteric ligands
Szarka, Á.b and Gabellieri, E.c and Gonnelli, M.c and Cioni, P.c and Lakos, Z.a and Somogyi, B.a
Journal of photochemistry and photobiology. B, Biology (Print), 1998
DOI: 10.1016/S1011-1344(97)00119-X
PRESSURE EFFECTS ON PROTEIN FLEXIBILITY MONOMERIC PROTEINS
CIONI, P; STRAMBINI, GB
Journal of Molecular Biology, 1994
DOI: 10.1006/jmbi.1994.1579
Heterogeneity of protein conformation in solution from the lifetime of tryptophan phosphorescence
Cioni, P. and Gabellieri, E. and Gonnelli, M. and Strambini, G.B.
Biophysical chemistry (Print), 1994
CHARACTERIZATION OF TRYPTOPHAN PHOSPHORESCENCE OF ASPARTATE-AMINOTRANSFERASE FROM ESCHERICHIA-COLI
CIONI, P; ONUFFER, JJ; STRAMBINI, GB
European journal of biochemistry (Print), 1992
DOI: 10.1111/j.1432-1033.1992.tb17345.x
Relationship of disulfide bonds to the maintenance of the active secondary structure of alfalfa (Medicago sativa ) leaves protease inhibitor
Gonnelli, M. and Balestreri, E. and Romagnoli, A. and Fissi, A. and Cioni, P. and Gabellieri, E. and Felicioli, R.
Journal of agricultural and food chemistry, 1986
Purification and characterization of two leaf polypeptide inhibitors of leaf protease from alfalfa (Medicago sativa)
Gonnelli, M.a and Cioni, P.a and Romagnoli, A.a and Gabellieri, E.a and Balestreri, E.a and Felicioli, R.b
Archives of biochemistry and biophysics (Print), 1985