Federica Viti
Research staff
Member of IBF Advisory Board
Since 2018: Researcher @ National Research Council - Institute of Biophysics (Genova - Italy)
2018: Collaborator @ Italian Institute of Tecnnology (Genova - Italy)
2014 - 2018: Researcher @ National Research Council - Institute of Biophysics (Genova - Italy)
2010-2013: Post-doc positions @ National Research Council - Institute for Biomedical Technologies (Milano - Italy)
2006 - 2009: PhD in Bioengineering @ National Research Council - Institute for Biomedical Technologies (Milano - Italy) & University of Genova (Genova - Italy)
2004 - 2005: Collaborator @ National Research Council – Institute for Biomedical Technologies (Milano - Italy)
2004: Degree in Biomedical Engineering @ University of Genova (Genova - Italy)
Activity in short
Main scientific activities regard Bioinformatics, with specific interest for analysis of data produced by genomic and transcriptomics high-throughput approaches, and Mechanobiology, in particular regarding biomechanics characterization of cells. In addition, I developed interests on application of technology to biological and biomedical fields, exploiting my bioengineering background.
orcid://0000-0002-9651-8896,
Contact:
- Email federica.viti@ibf.cnr.it
- Phone +39-010-6475233
- Location Genova
Website:
http://users.ge.ibf.cnr.it/smml
Research interests:
- Bioinformatics (Principal investigator)
- Mechanobiology (Principal investigator)
- BioPlastics Europe
Further collaborations:
- - Present and/or past collaborations with personnel from other CNR Institutes (ITB in Milano, IMATI in Genova, IEIIT in Genova, IAS in Ganova, IGM in Pavia)
- - University of Genova (DIBRIS - UniGe)
- - University of Glasgow (UK)
- - Ospedale San Martino (IRCCS) in Genova
- - Institute Giannina Gaslini (IRCCS) in Genova
- - Italian Institute of Technology (IIT)
Financial support:
- Project "Approccio combinato di genetica molecolare e morfo-meccanica cellulare: uno studio pilota volto allo sviluppo di un possibile trattamento della miopatia viscerale (CIPO)" funded by Fondazione Alessandra Bono (2020-2021)
-
- Project "Sensori wireless miniaturizzati a basso consumo per l’integrazione in dispositivi indossabili di monitoraggio bio-funzionale" (RLFO18ASSRIC/72/1) on the call "POR-FSE Liguria 2014-2020" funded by the Liguria Region (2020-2022)
-
- Project "Utilizzo di High Resolution Melting su piattaforma embedded per l’analisi di microsatelliti finalizzata all’identificazione univoca dell’individuo" (RLFO18ASSRIC/73/1) on the call “POR-FSE Liguria 2014 2020” funded by the Liguria Region (2019-2021)
-
- Project "Whole Genome Sequencing into the diagnostic workflow of rare diseases: a cost-effectiveness evaluation in a heterogeneous population of patients with inconclusive Whole Exome" (RF-2018-12366314) on the call “Ricerca Finalizzata 2018” funded by the Italian Ministry of Health (2020-2023)
-
- Project "Sviluppo di una piattaforma per lo studio della meccanotrasduzione: dalla singola molecola alla cellula vivente" (RBFR13V4M2) on the call "Futuro in Ricerca 2013" funded by the Italian Ministry of Education, University and Research (2014-2018)
Key publications:
A. Bartolozzi, F. Viti, S. De Stefano, F. Sbrana, L. Petecchia, P. Gavazzo, M. Vassalli. Development of label-free biophysical markers in osteogenic maturation. Journal of the Mechanical Behavior of Biomedical Materials. 2020. doi.org/10.1016/j.jmbbm.2019.103581. PMID: 32090910
R. Alfieri, M. Vassalli, F. Viti. Flow-induced mechanotransduction in skeletal cells. Biophysical Reviews. 2019. doi: 10.1007/s12551-019-00596-1. PMID: 31529361
F. Viti, M. Landini, A. Mezzelani, L. Petecchia, L. Milanesi, S. Scaglione. Osteogenic Differentiation of MSC through Calcium Signaling Activation: Transcriptomics and Functional Analysis. PlosOne. 2016. doi: http://dx.doi.org/10.1371/journal.pone.0148173. PMID: 2682858
D. Corrada, F. Viti, I. Merelli, C. Battaglia, L. Milanesi. myMIR: a genome-wide microRNA targets identification and annotation tool. Briefings in Bioinformatics. 2011. doi: 10.1093/bib/bbr062. PMID: 22021901
E. Mosca, R. Alfieri, I. Merelli, F. Viti, A. Calabria, L. Milanesi. A multilevel data integration resource for breast cancer study. BMC Syst Biology. 2010 doi: 10.1186/1752-0509-4-76.
PMID: 20525248
Publications (25):
Development of label-free biophysical markers in osteogenic maturationBartolozzi Alice; Viti Federica; De Stefano Silvia; Sbrana Francesca; Petecchia Loredana; Gavazzo Paola; Vassalli Massimo
Journal of the mechanical behavior of biomedical materials (Print), 2020
DOI: 10.1016/j.jmbbm.2019.103581
Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes
La Sala G.; Olieric N.; Sharma A.; Viti F.; de Asis Balaguer Perez F.; Huang L.; Tonra J.R.; Lloyd G.K.; Decherchi S.; Diaz J.F.; Steinmetz M.O.; Cavalli A.
Chem (Cambridge. Print), 2019
DOI: 10.1016/j.chempr.2019.08.022
Flow-induced mechanotransduction in skeletal cells
Alfieri R, Vassalli M, Viti F.
Biophysical reviews (Print), 2019
DOI: 10.1007/s12551-019-00596-1
A biophysical approach to quantify skeletal stem cells trans-differentiation as a model for the study of osteoporosis
Petecchia L, Viti F, Sbrana F, Vassalli M, Gavazzo P
Biophysical chemistry (Print), 2017
DOI: 10.1016/j.bpc.2017.05.011
Controlled single-cell cyclic compression and transcription analysis: A pilot study
Gavazzo P, Petecchia L, Facci P, Vassalli M, Viti F
Biophysical chemistry (Print), 2017
DOI: 10.1016/j.bpc.2017.07.010
Generation of a Functional Human Neural Network by NDM29 Overexpression in Neuroblastoma Cancer Cells
Alloisio S, Garbati P, Viti F, Dante S, Barbieri R, Arnaldi G, Petrelli A, Gigoni A, Giannoni P, Quarto R, Nobile M, Vassalli M, Pagano A
Molecular neurobiology, 2017
DOI: 10.1007/s12035-016-0161-3
OvMeter: an automated 3D-integrated opto-electronic system for Ostreopsis cf. ovata bloom monitoring
Sbrana F, Landini E, Gjeci N, Viti F, Ottaviani E, Vassalli M
Journal of applied phycology, 2017
DOI: 10.1007/s10811-017-1069-7
Osteogenic differentiation of MSC through calcium signaling activation: transcriptomics and functional analysis
F. Viti, M. Landini, A. Mezzelani, L. Petecchia, L. Milanesi, S. Scaglione
PloS one, 2016
DOI: 10.1371/journal.pone.0148173
The biophysics of piezo1 and piezo2 mechanosensitive channels
Soattin L.; Fiore M.; Gavazzo P.; Viti F.; Facci P.; Raiteri R.; Difato F.; Pusch M.; Vassalli M.
Biophysical chemistry (Print), 2016
DOI: 10.1016/j.bpc.2015.06.013
Guidelines for managing data and processes in bone and cartilage tissue engineering
Viti, Federica; Scaglione, Silvia; Orro, Alessandro; Milanesi, Luciano
BMC bioinformatics, 2014
DOI: 10.1186/1471-2105-15-S1-S14
SNPranker 2.0: a gene-centric data mining tool for diseases associated SNP prioritization in GWAS
Merelli, Ivan; Calabria, Andrea; Cozzi, Paolo; Viti, Federica; Mosca, Ettore; Milanesi, Luciano
BMC bioinformatics, 2013
DOI: 10.1186/1471-2105-14-S1-S9
Ontology-based resources for bioinformatics analysis.
Viti F., Merelli I, Calabria A., Cozzi P., Mosca E.,Alfieri R., Milanesi L.
International journal of metadata, semantics and ontologies (Online), 2012
IBDsite: a Galaxy-interacting, integrative database for supporting inflammatory bowel disease high throughput data analysis.
Merelli I , Viti F , Milanesi L.
BMC bioinformatics, 2012
IBDsite: a Galaxy-interacting, integrative database for supporting inflammatory bowel disease high throughput data analysis
Merelli I, Viti F, Milanesi L
BMC bioinformatics, 2012
DOI: 10.1186/1471-2105-13-S14-S5
myMIR: a genome-wide microRNA targets identification and annotation tool
Corrada, Dario; Viti, Federica; Merelli, Ivan; Battaglia, Cristina; Milanesi, Luciano
Briefings in bioinformatics, 2011
DOI: 10.1093/bib/bbr062
A multilevel data integration resource for breast cancer study
Mosca E.; Alfieri R.; Merelli I.; Viti F.; Calabria A.; Milanesi L.
BMC systems biology, 2010
DOI: 10.1186/1752-0509-4-76
SNPRanker: a tool for identification and scoring of SNPs associated to target genes.
Calabria A., Mosca E., Viti F., Merelli I., Milanesi L.
Journal of integrative bioinformatics, 2010
DOI: 10.2390/biecoll-jib-2010-138
Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
Viti F.; Merelli I.; Timmermans M.; den Bakker M.; Beltrame F.; Riegman P.; Milanesi L.
BMC bioinformatics, 2010
DOI: 10.1186/1471-2105-11-566
SNPRanker: a tool for identification and scoring of SNPs associated to target genes.
Calabria, Andrea; Mosca, Ettore; Viti, Federica; Merelli, Ivan; Milanesi, Luciano
Journal of integrative bioinformatics, 2010
DOI: 10.1515/jib-2010-138
Ontology-based, Tissue MicroArray oriented, image centered tissue bank
Viti, Federica; Merelli, Ivan; Caprera, Andrea; Lazzari, Barbara; Stella, Alessandra; Milanesi, Luciano
BMC bioinformatics, 2008
DOI: 10.1186/1471-2105-9-S4-S4
Ontology-based, Tissue MicroArray oriented, image centred tissue bank
Viti Federica, Ivan Merelli, Andrea Caprera, Barbara Lazzari, Alessandra Stella, Luciano Milanesi
BMC bioinformatics, 2008
A Grid based solution for Management and Analysis of Microarrays in distributed experiments
Porro I; Torterolo L; Corradi L; Fato M; Papadimitropoulos A; Scaglione S; Schenone A; Viti F
BMC bioinformatics, 2007
Tissue MicroArray: a distributed Grid approach for image analysis.
Viti F., Merelli I., Galizia A., D'Agostino D., Clematis A., Milanesi L.
Studies in health technology and informatics (Online), 2007
Strategies for comparing gene expression profiles from different microarray platforms: Application to a case-control experiment
Severgnini M, Bicciato S, Mangano E, Scarlatti F, Mezzelani A, Mattioli M, Ghidoni R, Peano C, Bonnal R, Viti F, Milanesi L, De Bellis G, Battaglia C
Analytical biochemistry (Print), 2006
A simple non invasive computerized method for the assessment of bone repair within osteoconductive porous bioceramic grafts
Francesco Beltrame; Ranieri Cancedda; Barbara Canesi; Antonio Crovace; Maddalena Mastrogiacomo; Rodolfo Quarto; Silvia Scaglione; Carmela Valastro; Federica Viti
Biotechnology and bioengineering (Online), 2005