Mauro Manno


From 2001 to present: researcher at CNR-IBF; author of one patent and various publications on peer reviewed journals, book chapters and conference proceeding, most as first or corresponding author (H-index: 21).
2017: Le Studium Fellow at Univ. Orléans/CNRS-ICOA, Orléans (France); Award from the SMART LOIRE VALLEY Fellowships Program, funded by H2020-MSCA Action.
2010: Visiting scientist at CIMR, University of Cambridge (UK).
2000: PhD in Physics, University of Palermo.
1998: Visiting Scientist at M.I.T., Cambridge, MA (USA).
1996: Laurea (MD) in Physics, University of Palermo (110/110 cum laude).

orcid://0000-0001-9843-0428, ncbi://56463429


- Email
- Phone +39-091-6809305
- Site Palermo


Research interests:

- Molecular bases od serpinopathies (Principal investigator)

- Characterisation of extracellular vescicles (Principal investigator)

- Laboratory for Advanced and Scattering Technologies (LAST) (Principal investigator)

- Production, Purification, Mutagenesis and Characterization of proteins expressed in E. coli

- Model Membrane Systems and Interaction Studies

Further collaborations:

- Elena Miranda (Università di Roma “La Sapienza”, Roma, Italy)
- Anna Fra (Università di Brescia, Brescia, Italy)
- Stefano Ricagno (Università di Milano, Milano, Italy)
- Sonia Caccia, Marco Cicardi (Università di Milano, Milano, Italy)
- James Irwing (UCL, London, UK)
- Irene Martinez (University of Murcia, Murcia, Spain)
- Richard Daniellou (University of Orléans-CNRS ICOA, Orléans, France)
- Antonio Emanuele (Università di Palermo, Palermo, Italy)
- Christopher J. Roberts (University of Delaware, Newark DE, USA)
- Riccardo Alessandro (Università di Palermo, Palermo, Italy)
- Antonella Bongiovanni. (CNR-IBIM, Palermo, Italy)
- Gabriella Pocsfalvi (CNR-IBBR, Napoli, Italy)
- Annamaria Kisslinger (CNR-IEOS, Napoli, Italy)
- Giovanna Liguori (CNR-IGB, Napoli, Italy)
- Paolo Arosio (ETH Zurich, Zurich, Switzerland)
- Nicolas Touzet (ITSligo, Sligo, Ireland)
- Katarina Landfester (Max Planck-MPIP, Mainz, Germany)
- Veronica Iglic (university of Ljubliana, Ljubliana, Slovenia)
- Laura Corcuera (Zabala Innovation Consulting, Pamplona, Spain)

Financial support:

- Extracellular vesicles from a natural source for tailor-made nanomaterials (Ves4US). Funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N. 801338. Period: 09/2018-08/2021.
- Percorsi formativi nei settori Biotecnologia, Biomedicina e Agroalimentare. Funding fromPO Sicilia FSE 2014-2020. Period: 04/2018-10/2019.
- Molecular and Cellular Bases of Serpin Conformational Diseases. Funding from Fondazione Cariplo, Project N. 2013-0967. Period: 04/2014-12/2016.

Key publications:

Romancino DP, Buffa V, Caruso S, Ferrara I, Raccosta S, Notaro A, Campos Y, Noto R, Martorana V, Cupane A, Giallongo A, d’Azzo A, Manno M, Bongiovanni A (2018) Palmitoylation is a post-translational modification of Alix regulating the membrane organization of exosome-like small extracellular vesicles. Biochim Biophys Acta - General Subjects 1862:2879-2887

Noto R, Santangelo MG, Levantino M, Cupane A, Mangione MR, Parisi D, Ricagno S, Bolognesi M, Manno M, Martorana M (2015) Functional and dysfunctional conformers of human neuroserpin characterized by optical spectroscopies and Molecular Dynamics. Biochim Biophys Acta - Proteins and Proteomics 1854:110-117

Noto R, Santangelo MG, Ricagno S, Mangione MR, Levantino M, Pezzullo M, Martorana V, Cupane A, Bolognesi M, Manno M (2012) The tempered Polymerization of Numan Neuroserpin. PLoS ONE 8:e67713

Raccosta S, Martorana V, Manno M (2012) Thermodynamic versus Conformational Metastability in Fibril-Forming Lysozyme Solutions. J Phys Chem B 40:12078-12087

Manno M, Craparo EF, Podestà A, Bulone D, Carrotta R, Martorana V, Tiana G, San Biagio PL (2007) Kinetics of Different Processes in Human Insulin Amyloid Formation. J Mol Biol 366:258 274

Publication list