Debora Baroni

Researcher

Degree in biology (2001), PhD in Pharmacology and clinical toxicology (2005)

orcid://0000-0001-8764-2468, ncbi://56481858

Contact:

- Email debora.baroni@ibf.cnr.it
- Phone +39-010-6475555
- Site Genova

Research interests:

- Molecular pharmacology of cystic fibrosis

- Genetic diseases caused by mutations of the auxiliary subunits of the sodium channel

Financial support:

- Dissecting the rescue mechanisms mediated by CFTR correctors. Progetto 3#2018, Fondazione per la ricerca sulla fibrosi Cistica

Key publications:

Cossu C, Fiore M, Baroni D, Capurro V, Caci E, Garcia-Valverde M, Quesada R, Moran O. Anion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis Therapy. Front Pharmacol. 2018 Aug 7;9:852. doi: 10.3389

Baroni D, Picco C, Moran O. A mutation of SCN1B associated with GEFS+ causes functional and maturation defects of the voltage-dependent sodium channel. Hum Mutat. 2018 Jul 10. doi: 10.1002

Baroni D, Picco C, Moran O. Mutation E87Q of the beta1-subunit impairs the maturation of the cardiac voltage-dependent sodium channel. Sci Rep. 2017 Sep 6;7(1):10683. doi: 10.1038

Baroni D, Zegarra-Moran O, Moran O. Functional and pharmacological induced structural changes of the cystic fibrosis transmembrane conductance regulator in the membrane solved using SAXS. Cell Mol Life Sci. 2015 Apr;72(7):1363-75. Doi: 10.1007

Barbieri R, Baroni D, Moran O. Identification of an intra-molecular disulfide bond in the sodium channel beta1-subunit. Biochem Biophys Res Commun. 2012 Apr 6;420(2):364-7. doi: 10.1016

Publication list