Anno2012
AutoriMinati L; Antonini V; Dalla Serra M; Speranza G
AbstractBranched gold nanoparticles were grown on oxidized multiwalled carbon nanotubes by one-step reduction of gold chloride in water. The carbon nanotube/gold hybrids were used for the delivery of the anticancer drug doxorubicin hydrochloride into A549 lung cancer cell line. Doxorubicin (Dox) can be adsorbed in high quantity on both inner and outer surfaces of oxidized carbon nanotubes by ?-? stacking interactions between doxorubicin aromatic groups and carbon nanotube (CNT) backbone. Carbon nanotube/gold hybrids display a broad absorption band in the red and near-infrared regions allowing their use for imaging applications. In vitro cellular tests showed that the nanostructures can efficiently transport and deliver doxorubicin inside the cells.
RivistaLangmuir
ISSN
Impact factor
Volume28
Pagina inizio15900
Pagina fine15906
Autori IBFMauro DALLA SERRA, Valeria ANTONINI
Linee di Ricerca IBFMD.P01.028.001
Sedi IBFIBF.TN