Anno2011
AutoriThiel G, Baumeister D, Schroeder I, Kast SM, Van Etten JL, Moroni A
AbstractSome algal viruses contain genes that encode proteins with the hallmarks of K(+) channels. One feature of these proteins is that they are less than 100 amino acids in size, which make them truly minimal for a K(+) channel protein. That is, they consist of only the pore module present in more complex K(+) channels. The combination of miniature size and the functional robustness of the viral K(+) channels make them ideal model systems for studying how K(+) channels work. Here we summarize recent structure/function correlates from these channels, which provide insight into functional properties such as gating, pharmacology and sorting in cells.
RivistaBiochimica Et Biophysica Acta-biomembranes
ISSN
Impact factor4
Volume1808
Pagina inizio580
Pagina fine588
Autori IBFAnna MORONI
Linee di Ricerca IBFMD.P01.005.001
Sedi IBFIBF.MI