Anno2010
AutoriRicca ME, Foderà V, Giacomazza D, Leone M, Spadaro G, Dispenza C
AbstractPoly(N-vinyl-2-pyrrolidone) (PVP) hydrogels have been synthesised from the aqueous solutions of the same linear polymer by two different radiation sources: electron beams and UV rays. The present investigation couples conventional hydrogel characterisation techniques with the study of the partition equilibria, fluorescence behaviour and release of two different molecular probes, 1-anilino-8-naphthalene sulphonate (ANS) and Thioflavin T (ThT). The two probes have comparable molecular weight and different structural and optical properties. The ‘chemical’ networks produced upon irradiation in different experimental conditions presented quite distinctive mechanical spectra, yielded to different porous solids upon freeze-drying and showed specific rehydration ratios when ‘equilibrated’ in water. More interestingly, they offered ‘hydrophobic pockets’ to host the ANS molecules in a way that the probe is completely occluded from water, making it fluoresce. Conversely, the generated PVP networks did not show any specific affinity towards the hydrophilic ThT that was only barely untaken.
RivistaColloid And Polymer Science
ISSN
Impact factor
Volume288
Pagina inizio969
Pagina fine980
Autori IBFDaniela GIACOMAZZA, Maurizio LEONE
Linee di Ricerca IBFMD.P01.002.001
Sedi IBFIBF.PA