Anno2016
AutoriOssola D, Dörig P, Vörös J, Zambelli T, Vassalli M
AbstractAtomic force microscopy (AFM) cantilevers have proven to be very effective mass sensors. The attachment of a small mass to a vibrating cantilever produces a resonance frequency shift that can be monitored, providing the ability to measure mass changes down to a few molecules resolution. Nevertheless, the lack of a practical method to handle the catch and release process required for dynamic weighting of microobjects strongly hindered the application of the technology beyond proof of concept measurements. Here, a method is proposed in which FluidFM hollow cantilevers are exploited to overcome the standard limitations of AFM-based mass sensors, providing high throughput single object weighting with picogram accuracy. The extension of the dynamic models of AFM cantilevers to hollow cantilevers was discussed and the effectiveness of mass weighting in air was validated on test samples.
RivistaNanotechnology (bristol, Online)
ISSN1361-6528
Impact factor
Volume27
Pagina inizio
Pagina fine
Autori IBFMassimo VASSALLI
Linee di Ricerca IBFMD.P01.001.001
Sedi IBFIBF.GE