AutoriTodaro S, Sabatino MA, Mangione MR, Picone P, Di Giacinto ML, Bulone D, Dispenza C
AbstractPartially degalactosylated xyloglucan from tamarind seeds (Deg-XG) is a very appealing biopolymer for the production of in situ gelling systems at physiological temperature. In this work, we observe that the morphology of hydrogels evolves towards high degrees of structural organization with time, yielding to dense stacks of thin membranes within 24 h of incubation at 37 °C. We also explore the possibility offered by gamma irradiation of controlling the time scale of this phenomenon, the final morphology and mechanical properties of the system. Structural and molecular modifications of Deg-XG with dose are investigated by FTIR, dynamic light scattering (DLS) and rotational viscosimetry. The impact on gelation ability and gel strength is studied by rheological analysis. The morphology evolution is investigated by SEM analysis, and absence of cytotoxicity verified by MTS assay and optical microscopy of neuroblastoma cells.
RivistaCarbohydrate Polymers
Impact factor
Pagina inizio382
Pagina fine390
Autori IBFDonatella BULONE, Maria Rosalia MANGIONE
Linee di Ricerca IBFMD.P01.002.001